}{\rtlch\fcs1 \af0 \fs18\cf1\insrsid2702633\charrsid2702633 \~ \cf1\insrsid2702633\charrsid2702633 \~telomeres.\line }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf15\insrsid2702633\charrsid2702633 D.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~DNA hubs. \cf1\insrsid2702633\charrsid2702633 \~\line }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\cf1\insrsid2702633\charrsid2702633 A. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~ }{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 45,X\line }{\rtlch\fcs1 \af0 \ltrch\fcs0 [5], Chromosomes were first observed in plant cells by Carl Wilhelm von Nägeli in 1842. }{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 \~ {\fdbmajor\f31526\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese);}{\fhimajor\f31528\fbidi \froman\fcharset238\fprq2 Cambria CE;}{\fhimajor\f31529\fbidi \froman\fcharset204\fprq2 Cambria Cyr;} Aneuploidy may also occur within a group of closely related species. \par }\pard \ltrpar\ql \li0\ri0\sb319\sa319\keep\keepn\nowidctlpar\wrapdefault\faauto\rin0\lin0\itap0\pararsid11028655 {\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 18.\~To observe chromosomes, they must be\~\line }{\rtlch\fcs1 \af0 }{\rtlch\fcs1 \par }\pard \ltrpar\ql \li0\ri0\keep\keepn\nowidctlpar\wrapdefault\faauto\rin0\lin0\itap0 {\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 \~ \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~ }{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 samples amniotic fluid.\line }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf15\insrsid2702633\charrsid2702633 B. Karyotyping of the parents is needed in order to provide genetic counseling. }{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 Copyright © 2020 Elsevier B.V. or its licensors or contributors. 9e7ef3f2d117d57859c6fffac327bffcfc793510d26726ce8b2f9ffcf6ecc98baf3efdfdbb4715f04d814765f890c644a29be408edf3181433567125272371be \par }{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 \line }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 14.\~ }{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 When they looked at the karyotype of the closely related Indian muntjac, Muntiacus muntjak, they were astonished to find it had female = 6, male = 7 chromosomes.[31]. }{\rtlch\fcs1 \af0 \ltrch\fcs0 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~population genetics. Idiogram of common marmoset (Callithrix jacchus) karyotype with human synteny. The sex of an unborn fetus can be determined by observation of interphase cells (see amniotic centesis and Barr body). }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~XXY}{\rtlch\fcs1 \af0\afs18 \ltrch\fcs0 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~Robertsonian translocation.\line }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf15\insrsid2702633\charrsid2702633 B. Giemsa is specific for the phosphate groups of DNA. However, phenotypic and genotypic overlaps with EFT have been described. No reproduction or distribution without the prior written consent of McGraw-Hill Education. The risk of recurrence in a patient’s child could be as high as 50%, but no affected individuals are known to have reproduced to date. \rtlch\fcs1 \af0\afs18 \ltrch\fcs0 \fs18\cf1\insrsid2702633\charrsid2702633 Chorionic villus sampling reveals a fetus has the karyotype 47, XYY. \lsdsemihidden0 \lsdunhideused0 \lsdpriority60 \lsdlocked0 Light Shading Accent 4;\lsdsemihidden0 \lsdunhideused0 \lsdpriority61 \lsdlocked0 Light List Accent 4;\lsdsemihidden0 \lsdunhideused0 \lsdpriority62 \lsdlocked0 Light Grid Accent 4; 19.2). \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1033\langfe1033\cgrid\langnp1033\langfenp1033 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\cf1\insrsid2702633\charrsid2702633 Chapter 13}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\cf1\insrsid13633925 Elevated hCG, inhibin A, AFP, estradiol, and pregnancy-associated plasma protein\line }{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf15\insrsid2702633\charrsid2702633 C.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \cf1\insrsid2702633\charrsid2702633 \~}{\rtlch\fcs1 \af0\afs18 stains that distinguish AT-rich from GC-rich sequences. \par }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\cf1\insrsid2702633\charrsid2702633 Chromosomes

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