How the medicine is broken down by and discharged from the body, How much medicine is needed and how often, For a vaccine, researchers see if it causes the desired response from the body’s immune system, How much of the medicine or vaccine is needed and how often, Confirm that the medication or vaccine is effective, Compare the medicine or vaccine to commonly used treatments. V114 is an investigational vaccine currently being evaluated for its ability to provide protection against pneumococcal disease caused by serotypes contained in the vaccine. Our pipeline provides an overview of our late-stage clinical development programs and is updated quarterly. Private Securities Litigation Reform Act of 1995. While this pipeline chart remains on the company’s website the company assumes no duty to update the information to reflect subsequent developments. Risks and uncertainties include but are not limited to, general industry conditions and competition; general economic factors, including interest rate and currency exchange rate fluctuations; the impact of the recent global outbreak of novel coronavirus disease (COVID-19); the impact of pharmaceutical industry regulation and health care legislation in the United States and internationally; global trends toward health care cost containment; technological advances, new products and patents attained by competitors; challenges inherent in new product development, including obtaining regulatory approval; the company’s ability to accurately predict future market conditions; manufacturing difficulties or delays; financial instability of international economies and sovereign risk; dependence on the effectiveness of the company’s patents and other protections for innovative products; and the exposure to litigation, including patent litigation, and/or regulatory actions. The interactive pipeline of Merck shows what the company is currently working on and can be filtered based on different factors. The chart reflects the company research pipeline as of July 31, 2020. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements. Phase 2 clinical trials test the vaccine or medicine in approximately 100 to 500 volunteers. We are called MSD everywhere, except in the United States and Canada where we are known as Merck & Co Inc, Kenilworth, NJ USA. Merck Pipeline Q3 2020 Reflecting Pipeline to July 31, 2020. Phase 3 trials can take from one to four years to complete, depending on the disease, length of study and number of volunteers. In the case of medicines, volunteers usually have the disease or condition the investigational medicine is designed to treat. endstream endobj 1015 0 obj <>stream More information are available in our Privacy Statement. There can be no guarantees with respect to pipeline products that the products will receive the necessary regulatory approvals or that they will prove to be commercially successful. H�dQ�j�0}�W�G�J�J�N�ֲ���!�!���ę���w%;�00�s�=G�H�7��ovՀ�+}3��~�V��]v������ }�o_�A+>��Z4�pN-rd��Ma�9�YJ*/��'��/����Dd,�QQ(�)��i�Pc���: By continuing, you will be directed to a site intended only for residents of the United States and Canada. You have accessed https://www.emdgroup.com, but for users from your part of the world, we originally designed the following web presence https://www.merckgroup.com. 3 - Being developed as a monotherapy and in combination with KEYTRUDA. By sharing this content, you are consenting to share your data to this social media provider. Phase 3 clinical trials can test the medicine or vaccine in 1,000 to 5,000 patient volunteers. For further information on clinical trials, please refer to: http://clinicaltrials.gov/ct2/results?term=v114, Vericiguat (MK-1242) is an investigational stimulator of soluble guanylate cyclase (sGC) currently being evaluated in a Phase 2b clinical trial of Patients With Heart Failure and Preserved Ejection Fraction Suffering From Worsening Chronic Heart Failure. Researchers closely monitor patients at regular intervals to: The application has been submitted to the regulatory authorities for review. h�bbd``b`�$��E�!�`N qO ��@Bm���`dn�щ����0 �M� Candidates shown in Phase 3 include specific products and the date such candidate entered intoPhase 3 development. %%EOF endstream endobj 1012 0 obj <>/Metadata 44 0 R/OCProperties<>/OCGs[1021 0 R]>>/Outlines 69 0 R/PageLayout/SinglePage/Pages 1009 0 R/StructTreeRoot 88 0 R/Type/Catalog>> endobj 1013 0 obj <>/Font<>/Properties<>/XObject<>>>/Rotate 0/StructParents 0/Tabs/S/Type/Page>> endobj 1014 0 obj <>stream Select 'Show All Results' link to see additional results. Excluding the impact from foreign exchange, sales declined 5%. Merck pipeline July 31, 2020 1L, first-line treatment; 1L-M, first-line maintenance treatment; 2L, second-line treatment. Candidates shown in Phase 3 include specific products. Consequently, the company will not update the information contained in the presentation and investors should not rely upon the information as current or accurate after July 31, 2020. The trial often takes place in a hospital. You can change which cookies are set at any time - and find out more about them in our cookie policy. Copyright 2020 Merck KGaA, Darmstadt, Germany, This website uses 'cookies' to give you the best, most relevant experience. Using this website means you’re OK with this. 2 - Being developed in combination with KEYTRUDA. Updated July 31, 2020. This news release of Merck & Co., Inc., Kenilworth, N.J., USA (the “company”) includes “forward-looking statements” within the meaning of the safe harbor provisions of the U.S. In vaccine studies, the volunteers may be healthy or have diseases or conditions. Consequently, the company will not update the information contained in the website and investors should not rely upon the information as current or accurate after the presentation date. Phase 3 trials take place in hospitals, clinics or physician offices. }{$�:��ל"��(��_m��zy�Bz�L��9H���Vh� � c^�+����la�qF���T�Q[���,d��* �Ī�?��R��4?� O#��'�/^m���iZGa����ˮ�Kf�E2c�����P�!���QW�� �È��b��Ω I:���������ܜ��E���ݽ���cF����R�����+� ���= 1011 0 obj <> endobj {{ search.results.length }} matching results. The information contained in this website was current as of the date presented. You can change which cookies are set at any time - and find out more about them in our cookie policy. Pour améliorer la prise en charge du cancer, Merck a établi des partenariats avec des acteurs importants en cancérologie (issus de l'industrie, d'universités et de centres de traitement du cancer). What do the phases of clinical trials mean? Additional factors that could cause results to differ materially from those described in the forward-looking statements can be found in the company’s 2019 Annual Report on Form 10-K and the company’s other filings with the Securities and Exchange Commission (SEC) available at the SEC’s Internet site (www.sec.gov).

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